Senior Scientist

Job Title: Scientist – Viral & Aggregate Particle Analysis
Location: Leiden, The Netherlands
Assignment Type: Contract (8 months)
Start Date: ASAP

About the Company
A leading biotechnology organization focused on the development of viral vaccines, viral vectors, and recombinant proteins. With state-of-the-art capabilities spanning process and analytical development through clinical manufacturing, the company partners with global clients to accelerate biopharmaceutical innovation.

Role Summary
We are looking for a seasoned scientist experienced in viral and aggregate particle analysis to join the analytical development department of a fast-paced biotech environment.
This is a hands-on, project-driven position, ideal for someone who can take ownership of characterization activities for viral products and biologics — driving assay development, optimization, and data interpretation to support product understanding and process improvement.

Key Responsibilities

• Lead analytical activities focused on virus particle quantification, aggregation, and physicochemical characterization.

• Perform and interpret biophysical and microscopic assays such as:

  • Dynamic Light Scattering (DLS)

  • Nanoparticle Tracking Analysis (NTA)

  • Size-Exclusion Chromatography with MALS (SEC-MALS)

  • Transmission Electron Microscopy (TEM)

  • Analytical Ultracentrifugation (AUC)

• Develop, qualify, and transfer analytical methods for viral particle characterization.

• Support in-process and product characterization studies for viral vaccines and gene therapy vectors.

• Collaborate closely with Upstream, Downstream, and QC teams to ensure data-driven decision-making.

• Prepare detailed technical reports, method documentation, and client-ready summaries aligned with quality standards.

• Contribute scientific expertise during troubleshooting and process optimization efforts.

Profile Requirements

• MSc or PhD in Biochemistry, Biotechnology, Virology, or related field.

• 5–10 years of experience in analytical development or biophysical characterization within biotech or vaccine development.

• Strong technical background in DLS, NTA, SEC-MALS, TEM, and AUC.

• Solid understanding of virus structure, aggregation behavior, and formulation stability.

• Familiarity with GMP/GLP settings and regulated environments.

• Excellent communication, data interpretation, and documentation skills.

• Proactive, hands-on, and able to work independently in a dynamic project environment.

Contract Details

• Duration: 8 months (potential for extension)

• Location: Leiden area (on-site/hybrid depending on project phase)

• Start Date: Immediate