Senior Bioinformatician

 As a Senior / Principal Bioinformatician, you will lead hands-on analysis across spatial transcriptomics and single-cell omics to deliver clear, decision-ready insights for target discovery and validation. You’ll help set the standard for reproducible analysis and scalable workflows in a discovery R&D environment.

Key responsibilities:

• Own end-to-end analysis of spatial transcriptomics (including in situ approaches) and scRNA-seq

• Integrate spatial/single-cell results with additional internal and external datasets to strengthen hypotheses

• Drive target identification and prioritization (gene networks, pathways, candidate targets)

• Build and maintain reproducible pipelines and scalable workflows (not one-off scripts)

• Produce structured reporting and clear visualisations for scientific stakeholders

• Maintain strong data practices: documentation, version control, and robust data organisation
  
  

Essential Requirements

• MSc or PhD in Bioinformatics, Computational Biology, Data Science (or similar)

• 5+ years of experience in bioinformatics / computational biology (industry preferred)

• Strong hands-on experience with single-cell and/or spatial transcriptomics

• Advanced R and/or Python (clean, reusable code; workflow mindset)

• Strong statistics foundation (QC, differential analysis, modelling)

• Experience operating in cross-functional discovery teams and translating biology questions into analysis plans
  
  

Desirable Requirements

• Multi-omics integration (e.g., proteomics, genetics) and/or digital pathology exposure

• Workflow/infrastructure tooling (e.g., Nextflow, Docker, SQL, graph databases like Neo4j)

• ML/DL exposure for omics or target discovery support.
  
  
• Neuroscience/neuroinflammation/neurodegeneration domain exposure
  
  

Location: Belgium 
Start Date: Asap