Eli Lilly’s $3B Leiden Bio Science Park Facility
American pharma giant Eli Lilly and Company is investing $3 billion to build a state-of-the-art manufacturing facility in Katwijk, within the Leiden Bio Science Park. This new plant will focus on oral medicines – including Lilly’s much-anticipated oral GLP-1 weight-loss drug (orforglipron) – and other innovative therapies across cardiometabolic health, neuroscience, oncology, and immunology.
The facility is designed with advanced technologies, including paperless manufacturing, AI-driven analytics, dock-to-dock automation, and spray-dried dispersion, to streamline production and quality control. Construction is slated to begin in 2026, and the site is expected to start producing medicines by 2030.
Significantly, Lilly’s expansion will create approximately 500 high-skilled manufacturing jobs and about 1,500 construction jobs to strengthen the company’s global supply chain footprint in Europe. The Netherlands was chosen partly for its proximity to the European Medicines Agency and its skilled, multilingual workforce, reflecting confidence in the local ecosystem.
Tiofarma’s Future-Proof Laboratory Investment
Dutch CDMO Tiofarma, based in Oud-Beijerland, is also ramping up its capabilities. The company is investing in a new Quality Control (QC) laboratory with a forward-looking, “future-proof” design to support its growing pharmaceutical production.
In recent years, Tiofarma has expanded its facilities substantially, for example, commissioning a greenfield production plant that included 1,100 m² of new cleanroom space outfitted with the latest technologies and sustainable design features.
The modern QC lab investment follows this trend of ensuring that infrastructure is built for future needs, with an emphasis on cutting-edge equipment, compliance with stringent GMP standards, and sustainable operation. By bolstering its QC laboratory and production capacity, Tiofarma aims to continue delivering high-quality medicines, such as complex creams, ointments, and nasal sprays, efficiently to patients and partners. This future-proof approach in facility design means the QC lab will be adaptable to new regulations and analytical technologies, securing Tiofarma’s role in the supply chain for years to come.
AstraZeneca’s Sustainable Expansion in Nijmegen
Global biopharma leader AstraZeneca has announced a major expansion of its biologics production site in Nijmegen, with a $70 million investment dedicated to sustainable medicine manufacturing. The Nijmegen facility plays a central role in filling, inspection, and distribution of biologic medicines – from potential cancer therapies to vaccines for premature infants.
The expansion project will add a second flexible filling line to the site and boost the workforce from roughly 100 to around 130 employees. Notably, this investment will enable AstraZeneca to deliver new modalities such as antibody-drug conjugates (ADCs), reflecting a push into next-generation therapeutics. Sustainability is a core focus: the Nijmegen site already leads in AstraZeneca’s Ambition Zero Carbon program, having achieved a 99% reduction in greenhouse gas emissions by 2021 and operating a fully electric vehicle fleet. The new expansion aligns with these green goals, ensuring that increased production capacity comes with a minimal environmental footprint.
AstraZeneca’s growth in the Netherlands underscores the importance of public-private collaboration in keeping the country at the forefront of life sciences innovation. Local and regional agencies (Oost NL, NFIA, and the Province of Gelderland) actively supported the project, recognising that the presence of a global player contributes greatly to the “Pharma Delta” cluster in the Nijmegen-Oss region. This expansion not only brings additional jobs and manufacturing capability, but also reinforces the Netherlands’ reputation for sustainable pharma production and strong health ecosystems.