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Principal Scientist

Principal Scientist

LocationGeleen, Netherlands
Business SectorBiotechnology
Contact emailk.mabena@panda-int.com
Job ref20994
Published4 months ago
Principal Scientist

For our Geleen site, we are looking for a highly experienced professional and lead scientist in the field of mRNA in vitro transcription reaction (IVT) and associated downstream processing to support our mRNA innovation lab. Subject matter expert in specific area. Strong evidence for delivering on commitments and working collaboratively in cross-disciplinary teams. Solid appreciation of commercial requirements.

Key responsibilities
  • Representation: act as a deputy of the team manager when needed and support the process development management.
  • Leadership: provide strong scientific, technical and regulatory leadership at project level. Lead individual scientists and lab technicians on complex projects.
  • Projects: lead multi-disciplinary matrix teams on complex projects in the area of scientific expertise. Lead problem solving and lessons learned activities.
  • Scientific tasks: design advanced experimental plans and data analysis methods, write and review high quality reports.
  • Customer interactions: develop strong customer relationships.
  • Training: lead training activities in the area of expertise.

Key requirements
  • PhD in Biotechnology, Bioengineering, Chemical Engineering or Analytical Chemistry with 5-10 years of experience.
  • At least 3 years of GMP experience in the mRNA field.
  • Builds and leads lab scientists and research associates focused on the development of encapsulated mRNA.
  • In-depth knowledge of mRNA analytics for determination of mRNA yield and purity parameters such as mRNA integrity, dsRNA, residual Protein and DNA.
  • Experience in sequencing (MiSeq, Sanguer, etc), UHPLC, Fragment analyzer, immunoassays, plate-based assays, etc.
  • Experience in setting up high throughput techniques for evaluation of optimized IVT conditions and follow up parallel analytics an advantage

  • Start Date: ASAP
  • Location: Geleen, Netherlands
  • Permanent Contract
  • Full-time: 40 hours

Contact Khanyi Mabena on +31 2020 44502 or send your CV to her at k.mabena@panda-int.com.