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Preclinical Development Leader

Preclinical Development Leader

LocationCharleroi, Belgium
Business SectorBiotechnology
Contact email
Job ref22402
Publishedabout 2 months ago

Title:  Preclinical Development Leader
Location: Charleroi, Belgium
We are in search of a seasoned and visionary leader to direct and oversee preclinical research and nonclinical development activities for our client burgeoning portfolio of neurovascular-focused therapies. The ideal candidate will possess an in-depth understanding of drug discovery and development principles and a proven track record of success in leading preclinical teams.

  • Steer and lead all facets of preclinical development, encompassing a diverse range of product modalities (small molecules, antibodies, proteins, and viral or non-viral gene delivery systems)
  • Construct and manage a team of highly skilled preclinical scientists with a wide array of expertise
  • Formulate comprehensive and well-structured plans and budgets for the preclinical team
  • Contribute to crafting target product profiles and preclinical development strategies to advance assets from discovery through candidate selection and IND-enabling studies
  • Design, plan, and oversee in vivo pharmacology, safety, and toxicology studies
  • Nurture strong collaboration with internal and external research teams, ensuring alignment and maximizing the impact of the preclinical group
  • Establish and maintain collaborative partnerships with academic institutions and CROs
  • Oversee the development and documentation of study protocols, data review, analysis, and interpretation, ensuring timely reporting of outcomes
  • Provide insights and contribute to go/no-go decision-making, including the identification and selection of potential preclinical candidates
  • Proactively participate in issue-resolution teams, offering valuable contributions to hypothesis generation


  • A PhD in Pharmacology, Toxicology, or a related discipline, complemented by postdoctoral or equivalent experience
  • Over 10 years of proven industry experience in nonclinical assessment of novel therapeutics, preferably for a variety of product modalities targeting CNS disorders
  • A comprehensive grasp of drug discovery and development principles, coupled with a firm understanding of regulatory requirements
  • A demonstrable track record of leading nonclinical drug development programs (pharmacology, toxicology, formulation, regulatory, and DMPK) for small/large molecules and/or advanced therapy medicinal products
  • Expertise in designing and executing a wide range of animal model studies, particularly in the context of CNS disorders
  • Proven experience in managing and leading teams in a biotech environment
  • Exceptional interpersonal skills that foster a positive and collaborative work environment, coupled with diplomatic and critical thinking abilities
  • Highly effective communication skills, with a demonstrated ability to communicate complex scientific concepts in both written and verbal forms
  • Strong analytical and problem-solving skills, with the ability to think critically and identify innovative solutions


  • Collaborate closely with the company's founders and a team of world-renowned scientists
  • Embark on a challenging and rewarding endeavour to advance innovative therapies for patients in need
  • Become a part of a highly motivated, international, and passionate team

Interested ? Contact Capucine at c.cornen@panda-int.com for more information.