Senior scientist for the Upstream Processing

Location Ghent , Belgium
Discipline: Biotechnology
Job type: Permanent
Contact name: Cherish Becker

Contact email: c.becker@panda-int.com
Job ref: 10422
Published: 4 months ago

One of my leading Biotech clients wishes to enforce its Biological Drug Substance (DS) development and production team with a Senior scientist for the Upstream Processing department starting from August 2020. He/she will be part of a team responsible for conducting activities in the field of process development and manufacturing of biologicals considering the regulatory requirements and clients’ needs. The activities are related to cell culture and fermentation. He/she will report to the Team Leader Upstream Processing of DS Biologicals.

 

YOUR RESPONSIBILITIES

  • As a senior scientist and being a member of the Upstream Processing group, you will be assigned to act as a lead scientist for one or more specific projects. This means review of scientific work, setting up and rework of experimental plans based on gathered results from project team and follow-up all upstream related activities. You will carry end responsibility towards the quality of output, results, reports and methods.
  • Develop microbial and mammalian cell culture processes including the harvesting procedure, and perform scale-up studies
  • Coordinate the transfer of the culture process to the cGMP facility
  • Ensure upstream process related Standard Operating Procedures, Batch Record Documents and reports are set-up. Write, review and approve production related documents/batch records
  • Coordinate and perform production runs in a cGMP or non-cGMP environment in accordance with the applicable requirements as described in procedures
  • Ensure the follow-up of critical process parameters, monitoring of the process parameters which may affect product quality
  • Maintain safe practices and work environment
  • Support the team in deviations and investigations
  • Communicate the status of operations to the Team Leader, Project Leader and team members
  • Internal and external communication of process results
  • Follow-up new technologies in the field and support strategic decisions concerning future investments
  • As senior scientist, you will be responsible over time for guiding one or multiple people in function of his/her assigned projects and act as a scientific mentor.

YOUR DETAILS

  • A PhD (or a Master Degree with 5 years of experience) with biological scientific orientation (Biochemistry, Bio-engineering, Industrial Engineering…) or related discipline with relevant expertise (production of biologics)
  • Knowledge about cGMP and current guidelines by regulatory instances is an asset
  • Experience with mammalian cell culture processes is highly recommended
  • You have a strong eye for detail (review of data)
  • You are keen on being present in a laboratory/production environment
  • Excellent organization and coordination skills
  • Flexible and creative (problem solver)
  • Excellent oral communication, reporting and presentation skills
  • Ability to work independently as well as a member of a team in a dynamic environment
  • Fluent in English and Dutch (written and spoken)???.

ORGANISATION

  • Work in a fast growing organization.
  • A position with responsibility within a dynamic company.
  • Personal development through learning on the job and additional external training.
  • A market oriented compensation.

INTERESTED?

For more information please contact me at: +31 (0)20 20 44 502 or c.becker@panda-int.com.

One of my leading Biotech clients wishes to enforce its Biological Drug Substance (DS) development and production team with a Senior scientist for the Upstream Processing department starting from August 2020. He/she will be part of a team responsible for conducting activities in the field of process development and manufacturing of biologicals considering the regulatory requirements and clients’ needs. The activities are related to cell culture and fermentation. He/she will report to the Team Leader Upstream Processing of DS Biologicals.

 

YOUR RESPONSIBILITIES

  • As a senior scientist and being a member of the Upstream Processing group, you will be assigned to act as a lead scientist for one or more specific projects. This means review of scientific work, setting up and rework of experimental plans based on gathered results from project team and follow-up all upstream related activities. You will carry end responsibility towards the quality of output, results, reports and methods.
  • Develop microbial and mammalian cell culture processes including the harvesting procedure, and perform scale-up studies
  • Coordinate the transfer of the culture process to the cGMP facility
  • Ensure upstream process related Standard Operating Procedures, Batch Record Documents and reports are set-up. Write, review and approve production related documents/batch records
  • Coordinate and perform production runs in a cGMP or non-cGMP environment in accordance with the applicable requirements as described in procedures
  • Ensure the follow-up of critical process parameters, monitoring of the process parameters which may affect product quality
  • Maintain safe practices and work environment
  • Support the team in deviations and investigations
  • Communicate the status of operations to the Team Leader, Project Leader and team members
  • Internal and external communication of process results
  • Follow-up new technologies in the field and support strategic decisions concerning future investments
  • As senior scientist, you will be responsible over time for guiding one or multiple people in function of his/her assigned projects and act as a scientific mentor.

YOUR DETAILS

  • A PhD (or a Master Degree with 5 years of experience) with biological scientific orientation (Biochemistry, Bio-engineering, Industrial Engineering…) or related discipline with relevant expertise (production of biologics)
  • Knowledge about cGMP and current guidelines by regulatory instances is an asset
  • Experience with mammalian cell culture processes is highly recommended
  • You have a strong eye for detail (review of data)
  • You are keen on being present in a laboratory/production environment
  • Excellent organization and coordination skills
  • Flexible and creative (problem solver)
  • Excellent oral communication, reporting and presentation skills
  • Ability to work independently as well as a member of a team in a dynamic environment
  • Fluent in English and Dutch (written and spoken)???.

ORGANISATION

  • Work in a fast growing organization.
  • A position with responsibility within a dynamic company.
  • Personal development through learning on the job and additional external training.
  • A market oriented compensation.

INTERESTED?

For more information please contact me at:  +31 (0)20 20 44 502 or c.becker@panda-int.com.